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Preimplantation Genetic Testing/ Pre-Implantation Genetic Diagnosis

Preimplantation genetic testing (PGT-A) is a screening test that can be performed on embryos created via in vitro fertilization (IVF) to genetically analyse the embryos prior to transfer.

Sperm Selection

Why PGS is Recommended?

  • One of the most common reasons that an embryo transfer does not result in a pregnancy is due to abnormal embryo genetics. PGT can ensure that the embryo selected for transfer has the correct number of chromosomes, thereby reducing the chances for a failed IVF cycle and reducing the chance of miscarriage


  • Pre-implantation genetic diagnosis (PGD) /PGT-Sr or PGT-M is a laboratory procedure used in conjunction with in vitro fertilization (IVF) to reduce the risk of passing on inherited conditions. Some of the most common reasons for PGD are specific single-gene conditions (such as cystic fibrosis or sickle cell anemia) and structural changes of a parent's chromosomes.


  • Typically, couples in need of these techniques are not infertile but have a family history of a condition and want to reduce the risk of having another child with significant health issues or early death. Through generally available genetic screening, however, occasionally couples who are seeking fertility treatment are found to be at risk of passing on an inherited condition, and PGD may be an option for them.


  • PGD is available for almost any inherited condition for which the exact mutation is known. A unique test must be developed for each couple, however. This test design may take up to several months to complete before beginning an IVF cycle.PGD uses IVF, in which multiple eggs are matured and retrieved. The oocytes are inseminated with sperm using intracytoplasmic sperm injection.


  • The resulting embryos are grown in culture until the Blasocyst stage, which is day five of embryo development. At this point, the embryo is biopsied with the removal of one to two cells. This process does not damage the cells remaining within the embryo.


  • The isolated cells are evaluated for specific genetic conditions. Embryos that are found to be unaffected are transferred back to the woman's uterus on day five of embryo development.


FAQ

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Researches have concluded that, in most cases, the major cause of infertility in females is attributed to stress and psychological factors. Stress can have a negative impact on sperm and egg production. Hence, it is important to take the help of an expert to manage stress and achieve the best treatment.

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A variety of factors can cause infertility, and the cause of infertility in every patient is different. Esha IVF, we provide a personalized treatment plan for couples that helps them achieve a successful pregnancy. Based on diagnosis (root cause), age, and health of the patient, the treatment is provided.

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When an IVF cycle is not successful, the most common cause is the embryo is not growing before implantation. There are various other factors that cause can IVF failure, like poor uterine receptivity and the use of poor quality of the embryo. A failed IVF can cause an emotional impact on one's health, but there are also other techniques that can help, like embryo donation and surrogacy program.

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The fertility workup will involve tests to determine if one is suffering from infertility issues and its causative agent:

  • Checking for hormone levels on specific days during the menstrual cycle.
  • Hysterosalpingogram or HSG is done to check for uterus and tubes shape.
  • Examination of cervical mucus.
  • HSG is done to check the shape of the uterus.
  • Analysis of sperm, shape, count, and motility.
  • ivf cost in india hyderabad

    If you want to become an egg donor, they need to be in a good state of health, and they also have to undergo a series of psychological screenings and physical screenings. Egg donation can help other infertile females to start their families. Females who age 21-33 years and those who are not suffering from genetic or other health concerns can become a suitable donor.

    ivf cost in india hyderabad

    Egg and sperm freezing can be beneficial for a number of reasons for women and men, those who are wishing to preserve their fertility for the future. It can be performed by males and females who want to delay childbearing in order to pursue an education and career, and also in case one is undergoing cancer treatment.

    ivf cost in india hyderabad

    Low ovarian reserve occurs when the ovaries lose their reproductive potential, and this can cause infertility. No treatment is effective to stop the process of low ovaries reserve, and in females who are infertile due to low egg count and quality, they can undergo ART (assisted reproductive technologies) to achieve a pregnancy.